Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL967954 | 0.80 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL29710452 | 0.80 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL627680 | 0.80 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7211578 | 0.80 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL2861818 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7636014 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7637712 | 0.75 | PBRM1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7642682 | 0.75 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4089006 | 0.75 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3685419 | 0.75 | CHRNB2 (0.35) | CHRNB2CHRNA4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105608-B2 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20050154139-A1 | Copolymer of propylene with a conjugated diene and a process of preparing the same | TONEN CHEMICAL CORPORATION (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-0914323-B1 | METALLOCENES AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6268518-B1 | AS POLYMERIZATION CATALYSTS FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-31 | — | — | US | disclosed |
| EP-0914323-A1 | METALLOCENES AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | Montell Technology Company B.V. (NL) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998043989-A1 | METALLOCENES AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-08 | — | — | WO | disclosed |