SCHEMBL587284

SCHEMBL587284

C=CCNOC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
MAPT P10636 3/20 0.50
POLB P06746 2/20 0.50
HPGD P15428 2/20 0.50
TSHR P16473 1/20 0.47
F2 P00734 1/20 0.45
TDP1 Q9NUW8 4/20 0.44
CYP3A4 P08684 3/20 0.44
MEN1 O00255 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.44
AKT1 P31749 1/20 0.42
MAPK1 P28482 2/20 0.42
HIF1A Q16665 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylamine SCHEMBL2830556 0.78 KMT2A (0.44) KMT2AALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL10061827 0.77 KMT2A (0.57) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL11567424 0.76 MAPT (0.43) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL9293455 0.76 CCNA2 (0.46) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL28958798 0.76 ALDH1A1 (0.55) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL3492756 0.76 TSHR (0.57) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL20415330 0.76 KMT2A (0.55) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL28852641 0.74 TSHR (0.43) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL10904247 0.74 KMT2A (0.53) KMT2AALDH1A1LMNAMAPTPOLB
SCHEMBL27954014 0.74 ALDH1A1 (0.53) KMT2AALDH1A1LMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110357989-A Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application 常州强力电子新材料股份有限公司 2019-10-22 CN claimed
EP-2475687-B1 A PHOTOINITIATOR COMPOSITION SUN CHEMICAL BV (NL) 2014-11-12 EP claimed
EP-0923597-B1 SUBSTITUTED PROPARGYLETHOXYAMIDO NUCLEOSIDES PE CORP NY (US) 2001-09-26 EP claimed
US-5770716-A CHAIN TERMINATING AND CHAIN EXTENDING NUCLEOTIDES, PRIMER EXTENSION REACTIONS, DNA SEQUENCING, POLYMERASE CHAIN REACTION THE PERKIN-ELMER CORPORATION (US) 1998-06-23 US claimed
JP-2161439-A None JP disclosed
JP-2161440-A None JP disclosed
CN-110357989-A Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application 常州强力电子新材料股份有限公司 2019-10-22 CN disclosed
CN-103430100-B Photosensitive resin composition, photoresist film using same, method for forming resist pattern, and method for forming conductor pattern 日兴材料株式会社 2016-08-17 CN disclosed
CN-104854199-A Active energy ray curable offset ink composition DIC GRAPHICS CORP 2015-08-19 CN disclosed
US-20140155356-A1 CURABLE BONE SUBSTITUTE A ENTERPRISES, INC. (US) 2014-06-05 US disclosed
EP-2238105-B1 NOVEL COMPOUNDS AS VANILLOID RECEPTOR ANTAGONISTS AMOREPACIFIC CORP (KR) 2014-04-16 EP disclosed
US-20140011881-A1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2014-01-09 US disclosed
WO-1998045310-A1 SUBSTITUTED PROPARGYLETHOXYAMIDO NUCLEOSIDES THE PERKIN-ELMER CORPORATION (US) 1998-10-15 WO disclosed
WO-1998045310-A1 SUBSTITUTED PROPARGYLETHOXYAMIDO NUCLEOSIDES THE PERKIN-ELMER CORPORATION (US) 1998-10-15 WO disclosed
US-5770716-A CHAIN TERMINATING AND CHAIN EXTENDING NUCLEOTIDES, PRIMER EXTENSION REACTIONS, DNA SEQUENCING, POLYMERASE CHAIN REACTION THE PERKIN-ELMER CORPORATION (US) 1998-06-23 US disclosed
US-5770716-A CHAIN TERMINATING AND CHAIN EXTENDING NUCLEOTIDES, PRIMER EXTENSION REACTIONS, DNA SEQUENCING, POLYMERASE CHAIN REACTION THE PERKIN-ELMER CORPORATION (US) 1998-06-23 US disclosed
JP-H02161440-A PHOTOPOLYMERIZABLE COMPOSITION DAICEL CHEM IND LTD 1990-06-21 JP disclosed
JP-H02161439-A PHOTOSENSITIZER AND PHOTOPOLYMERIZABLE COMPOSITION DAICEL CHEM IND LTD 1990-06-21 JP disclosed
US-4133890-A Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid THE DOW CHEMICAL COMPANY (US) 1979-01-09 US disclosed
US-4105791-A Hypolipidemic cycloalkylaminobenzoic acids THE DOW CHEMICAL COMPANY (US) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140011881-A1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME TRPV1, TRPA1, TRPV2 KMT2A 4592/4885ALDH1A1 787/4885LMNA 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.