Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710191 | 0.81 | NPSR1 (0.58) | GPR55GRM5GRM1NR1I2ADORA3 | |
| SCHEMBL4709468 | 0.73 | PDE2A (0.57) | GRM5GRM1OPRK1 | |
| SCHEMBL4709481 | 0.73 | GRM5 (0.47) | PDE4BGPR55GRM5GRM1GRIN1 | |
| SCHEMBL4707946 | 0.71 | GRM5 (0.46) | PDE4BGPR55GRM5GRM1GRIN1 | |
| SCHEMBL4709544 | 0.70 | NPSR1 (0.47) | THRBGPR55BCHEACHEGRM5 | |
| SCHEMBL5368722 | 0.69 | SIGMAR1 (0.47) | MAPK10GPR55NR1I2ADORA3HTR2C | |
| SCHEMBL5492932 | 0.67 | TP53 (0.60) | GPR55 | |
| SCHEMBL4709565 | 0.67 | NPSR1 (0.56) | GPR55GRM5GRM1NR1I2ADORA3 | |
| SCHEMBL11679315 | 0.67 | OPRK1 (0.67) | PTAFRNR1I2ADORA3HTR2CADRA1A | |
| SCHEMBL4710060 | 0.66 | TUBB4A (0.50) | PDE4BGRM5GRM1OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006509832-A | — | — | 2006-03-23 | — | — | JP | claimed |
| EP-1556055-A2 | USE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS HAVING A BENZODIAZEPINE STRUCTURE IN THERAPY | NEURO3D (FR) | 2005-07-27 | — | — | EP | claimed |
| WO-2004041258-A2 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS, PREPARATION AND USES | NEURO3D (FR) | 2004-05-21 | — | — | WO | claimed |