Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.52 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358176 | 0.86 | SCN9A (0.53) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| Oxalic Acid SCHEMBL6100151 | 0.83 | HTR6 (0.53) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL17429448 | 0.83 | BRD4 (0.41) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL24723379 | 0.81 | L3MBTL1 (0.46) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL27029550 | 0.80 | L3MBTL1 (0.49) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL558066 | 0.79 | SCN9A (0.61) | MEN1KMT2ACHRM2CHRM4CHRM1 | |
| SCHEMBL1196430 | 0.79 | L3MBTL1 (0.59) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL21246906 | 0.79 | L3MBTL1 (0.59) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL21259294 | 0.79 | L3MBTL1 (0.59) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL1196432 | 0.79 | L3MBTL1 (0.62) | L3MBTL1PIM1MARK3MAP4K2CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417122-A1 | INDOLE DERIVATIVES AND METHODS FOR ANTIVIRAL TREATMENT | PTC Therapeutics, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117932-A1 | INDOLE DERIVATIVES AND METHODS FOR ANTIVIRAL TREATMENT | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |