Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.72 |
| ▸ | SLC1A3 | P43003 | 7/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL28356659 | 1.00 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| D-Leucine SCHEMBL9449950 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL8568060 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| D-Leucine SCHEMBL9100148 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL8568063 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL25241602 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| D-Leucine SCHEMBL42012 | 0.85 | — | — | |
| Leucine SCHEMBL331557 | 0.85 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL20362356 | 0.85 | — | — | |
| Leucine SCHEMBL3888 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7090993-B2 | Method of assaying pyrrole-containing biological compounds | ROWETT RESEARCH INSTITUTE (GB) | 2006-08-15 | — | — | US | disclosed |
| US-7067267-B2 | Method of assaying pyrrole-containing biological compounds | ROWETT RESEARCH INSTITUTE (GB) | 2006-06-27 | — | — | US | disclosed |
| US-20040072370-A1 | Method of assaying pyrrole-containing biological compounds | ROWETT RESEARCH INSTITUTE (GB) | 2004-04-15 | — | — | US | disclosed |
| US-20040063222-A1 | Method of assaying pyrrole-containing biological compounds | ROWETT RESEARCH INSTITUTE (GB) | 2004-04-01 | — | — | US | disclosed |
| US-6667180-B2 | Detecting preferential particles in sample; obtain sample, incubate with label, determine amount of bound particles | ROWETT RESEARCH INSTITUTE (GB) | 2003-12-23 | — | — | US | disclosed |
| EP-1325339-A2 | METHOD OF ASSAYING PYRROLE-CONTAINING BIOLOGICAL COMPOUNDS | The Rowett Research Institute (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-20020048779-A1 | Method of assaying pyrrole-containing biological compounds | ROWETT RESEARCH INSTITUTE (GB) | 2002-04-25 | — | — | US | disclosed |
| WO-2002029409-A2 | METHOD OF ASSAYING PYRROLE-CONTAINING BIOLOGICAL COMPOUNDS | ROWETT RESEARCH INSTITUTE (GB) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072370-A1 | Method of assaying pyrrole-containing biological compounds | SHBG, HLA-B, LY96 | SLC7A5 4535/4885SLC1A3 4680/4885SLC1A2 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.