Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.57 |
| ▸ | TOP2A | P11388 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575143 | 0.81 | DPP4 (0.60) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| Hydrochloric Acid SCHEMBL10652952 | 0.81 | DPP4 (0.59) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL8844266 | 0.80 | DPP4 (0.63) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL9572096 | 0.79 | DPP4 (0.62) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL9146400 | 0.78 | DPP4 (0.63) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL5082609 | 0.78 | DPP4 (0.47) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL9378137 | 0.77 | DPP4 (0.59) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL9316567 | 0.77 | DPP4 (0.59) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL4247787 | 0.77 | DPP4 (0.68) | DPP4TOP2ATOP2BCHRM2DRD1 | |
| SCHEMBL10377708 | 0.77 | DPP4 (0.66) | DPP4TOP2ATOP2BCHRM2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012144-B2 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-14 | — | — | US | disclosed |
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | CYCS, CBR3, HCCS | DPP4 1704/4885TOP2A 257/4885TOP2B 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.