Phthalic Acid

Phthalic Acid

SCHEMBL5874347

CC(N)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
ALOX15 P16050 1/20 0.67
MAPT P10636 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
AKR1C3 P42330 2/20 0.52
KDM4E B2RXH2 4/20 0.50
HPGD P15428 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
HMGB1 P09429 1/20 0.50
CA6 P23280 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MYC P01106 3/20 0.48
NR4A1 P22736 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL9719105 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL27774192 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL29165245 0.90 ALDH1A1 (0.74) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28006650 0.88 ALDH1A1 (0.70) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Phthalic Acid SCHEMBL28418540 0.87 ALDH1A1 (0.78) ALDH1A1ALOX15MAPTHDAC8AKR1C3
Salicylic Acid SCHEMBL1835793 0.87 ALDH1A1 (0.72) ALDH1A1ALOX15MAPTHDAC8KDM4E
Phthalic Acid SCHEMBL28654022 0.86 ALDH1A1 (0.67) ALDH1A1ALOX15MAPTHDAC8AKR1C3
SCHEMBL1832663 0.86 ALDH1A1 (0.73) ALDH1A1ALOX15MAPTHDAC8AKR1C3
SCHEMBL1832988 0.86 CES2 (0.52) ALDH1A1ALOX15MAPTHDAC8CA12
Phthalic Acid SCHEMBL4758326 0.85 ALDH1A1 (0.82) ALDH1A1ALOX15MAPTHDAC8AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed