Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.38 |
| ▸ | KDM5C | P41229 | 3/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5875305 | 0.91 | GPR84 (0.52) | LMNACAMK2AGPR84FFAR1FFAR4 | |
| Glutarate SCHEMBL5874794 | 0.91 | SLC22A6 (0.50) | EGLN1LMNAALKBH5SUCNR1CAMK2A | |
| Sebacic Acid SCHEMBL5875432 | 0.89 | GPR84 (0.56) | LMNACAMK2AGPR84FFAR1FFAR4 | |
| Bicarbonate SCHEMBL2588842 | 0.87 | TSHR (0.35) | MAPK1TSHR | |
| Butyric Acid SCHEMBL5874271 | 0.87 | FFAR3 (0.54) | CAMK2AGPR84FFAR1FFAR4OR51E2 | |
| Malonic Acid SCHEMBL4864859 | 0.85 | LDHA (0.45) | CAMK2AMAPK1TSHR | |
| Oxalic Acid SCHEMBL5875016 | 0.84 | TSHR (0.33) | MAPK1OR51E2TSHR | |
| Valeric Acid SCHEMBL5874664 | 0.83 | AKR1B1 (0.50) | LMNACAMK2AGPR84FFAR1FFAR4 | |
| Propionic Acid SCHEMBL3844797 | 0.83 | FFAR3 (0.48) | TSHRALDH1A1FFAR3HDAC3HDAC1 | |
| Chloroacetic Acid SCHEMBL5874837 | 0.83 | TSHR (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240138403-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2024-05-02 | — | — | US | claimed |
| US-20230021295-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2023-01-19 | — | — | US | claimed |
| WO-2023278670-A1 | SYNERGISTIC COMBINATIONS FOR REDUCING VOLATILITY OF AUXIN HERBICIDES | ETHOX CHEMICALS, LLC (US) | 2023-01-05 | — | — | WO | claimed |
| US-20240138403-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2024-05-02 | — | — | US | disclosed |
| US-20230021295-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2023-01-19 | — | — | US | disclosed |
| WO-2023278670-A1 | SYNERGISTIC COMBINATIONS FOR REDUCING VOLATILITY OF AUXIN HERBICIDES | ETHOX CHEMICALS, LLC (US) | 2023-01-05 | — | — | WO | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0077674-A2 | Viscous compositions containing amidobetaines and salts | UNILEVER PLC (GB) | 1983-04-27 | — | — | EP | disclosed |
| US-4375421-A | COSMETICS, CLEANING COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1983-03-01 | — | — | US | disclosed |