Quinoline

Quinoline

SCHEMBL5874561

CCCCC(=O)O.c1ccc2ncccc2c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
CYSLTR2 Q9NS75 3/20 0.46
CYSLTR1 Q9Y271 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 2/20 0.45
HTT P42858 4/20 0.45
FAAH O00519 1/20 0.45
NPC1 O15118 1/20 0.44
HSP90AA1 P07900 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
PAX8 Q06710 1/20 0.44
RXFP1 Q9HBX9 2/20 0.43
PRNP P04156 1/20 0.43
MAPK10 P53779 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL5875240 0.95 ALDH1A1 (0.52) ALDH1A1FAAHKMT2AALOX15PPARG
Quinoline SCHEMBL29172160 0.95 ALDH1A1 (0.52) ALDH1A1FAAHKMT2AALOX15PPARG
Stearic Acid SCHEMBL27349245 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Decanoic Acid SCHEMBL5875354 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Octanoic Acid SCHEMBL5874863 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Stearic Acid SCHEMBL5875128 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Nonanoate SCHEMBL5874434 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Quinoline SCHEMBL5874680 0.94 GPR84 (0.50) ALDH1A1FAAHKMT2AALOX15PPARG
Quinoline SCHEMBL5874503 0.90 ALDH1A1 (0.57) ALDH1A1CYSLTR2CYSLTR1SMN1; SMN2LMNA
Adipic Acid SCHEMBL5875328 0.90 ALDH1A1 (0.61) ALDH1A1CYSLTR2CYSLTR1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed