Quinoline

Quinoline

SCHEMBL5874503

CCCC(=O)O.c1ccc2ncccc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RXFP1 Q9HBX9 4/20 0.45
PRNP P04156 2/20 0.45
MAPK10 P53779 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
KDM4E B2RXH2 2/20 0.44
RAB9A P51151 2/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
FFAR3 O14843 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HTT P42858 3/20 0.42
TSHR P16473 2/20 0.42
POLB P06746 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL5874561 0.90 ALDH1A1 (0.53) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL5874815 0.90 ALDH1A1 (0.65) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL4733766 0.90 ALDH1A1 (0.65) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL29172160 0.89 ALDH1A1 (0.52) ALDH1A1TSHRALOX15TDP1KMT2A
Quinoline SCHEMBL5875240 0.89 ALDH1A1 (0.52) ALDH1A1TSHRALOX15TDP1KMT2A
Quinoline SCHEMBL5874588 0.88 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL20524020 0.88 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL28864989 0.88 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2RXFP1PRNP
Quinoline SCHEMBL5874680 0.88 GPR84 (0.50) ALDH1A1TSHRALOX15TDP1KMT2A
Stearic Acid SCHEMBL5875128 0.88 GPR84 (0.50) ALDH1A1TSHRALOX15TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed