Quinoline

Quinoline

SCHEMBL5874588

CCC(=O)O.c1ccc2ncccc2c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PABPC1 P11940 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
PLK1 P53350 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
PRNP P04156 2/20 0.44
RXFP1 Q9HBX9 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
MGAM O43451 2/20 0.43
CYP3A4 P08684 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28864989 1.00 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL20524020 1.00 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL17372712 0.89 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL27931537 0.89 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL5874503 0.88 ALDH1A1 (0.57) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL28438613 0.87 ALDH1A1 (0.61) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL27725094 0.87 ALDH1A1 (0.61) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL5874979 0.87 ALDH1A1 (0.65) ALDH1A1LMNASMN1; SMN2PABPC1ALOX15
Quinoline SCHEMBL5874815 0.87 ALDH1A1 (0.65) ALDH1A1LMNASMN1; SMN2PABPC1HTT
Quinoline SCHEMBL4733766 0.87 ALDH1A1 (0.65) ALDH1A1LMNASMN1; SMN2PABPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed