Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDRD2HTR1BHTR1DHTR1F
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.39 |
| ▸ | TET3 | O43151 | 2/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL5874725 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2GPR84FFAR1SLC22A1 | |
| Malic Acid SCHEMBL20394029 | 0.84 | SMN1; SMN2 (0.79) | SMN1; SMN2GPR84FFAR1TET2TET3 | |
| Tetrapropylammonium SCHEMBL5874618 | 0.84 | CA4 (0.45) | SMN1; SMN2GPR84FFAR1SLC22A1MAPT | |
| Tetrylammonium SCHEMBL5874839 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2GPR84FFAR1TET2TET3 | |
| Malic Acid SCHEMBL11775907 | 0.82 | DNM1 (0.53) | SMN1; SMN2GPR84FFAR1SLC22A1 | |
| Malic Acid SCHEMBL28768725 | 0.82 | SMN1; SMN2 (0.83) | SMN1; SMN2GPR84FFAR1TET2TET3 | |
| Malic Acid SCHEMBL10573554 | 0.82 | SMN1; SMN2 (0.94) | SMN1; SMN2TET2TET3TET1MAPT | |
| Malic Acid SCHEMBL28325359 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2GPR84FFAR1TET2TET3 | |
| Malic Acid SCHEMBL1962148 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2GPR84FFAR1TET2TET3 | |
| Malic Acid SCHEMBL16934819 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2GPR84FFAR1TET2TET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |