Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDRD2HTR1BHTR1DHTR1F
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL11775907 | 0.90 | DNM1 (0.53) | SMN1; SMN2GPR84FFAR1SLC22A1 | |
| Tetrapropylammonium SCHEMBL5874615 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2GPR84FFAR1SLC22A1 | |
| Tetrabuthylammonium SCHEMBL5874730 | 0.85 | GPR84 (0.46) | SMN1; SMN2GPR84FFAR1SLC22A1 | |
| Cetrimonium SCHEMBL8437299 | 0.84 | DNM1 (0.52) | SMN1; SMN2GPR84FFAR1 | |
| Malic Acid SCHEMBL8437738 | 0.84 | DNM1 (0.52) | SMN1; SMN2GPR84FFAR1 | |
| Malic Acid SCHEMBL8437257 | 0.84 | DNM1 (0.52) | SMN1; SMN2GPR84FFAR1 | |
| Malic Acid SCHEMBL20394029 | 0.81 | SMN1; SMN2 (0.79) | SMN1; SMN2GPR84FFAR1 | |
| Cetyl Alcohol SCHEMBL14977021 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2GPR84FFAR1FFAR4 | |
| Stearic Acid SCHEMBL3379301 | 0.81 | GPR84 (0.65) | SMN1; SMN2GPR84FFAR1AKR1B1FFAR4 | |
| Tetrabuthylammonium SCHEMBL107243 | 0.81 | ACE2 (0.47) | GPR84FFAR1SLC22A1SLC22A2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5933693-A | Electroconductive elastic member and electrophotographic apparatus using same | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |