Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL5874730 | 0.89 | GPR84 (0.46) | CA4SMN1; SMN2GPR84SLC22A1FFAR1 | |
| Tetrapropylammonium SCHEMBL5874611 | 0.86 | CA4 (0.64) | CA4SLC22A1CYP3A4TSHRNFKB1 | |
| Tetrapropylammonium SCHEMBL5874615 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2GPR84SLC22A1MAPTSLC22A6 | |
| Tetrylammonium SCHEMBL5874843 | 0.84 | CA4 (0.48) | CA4SMN1; SMN2GPR84MAPTSLC22A6 | |
| Malic Acid SCHEMBL11775910 | 0.83 | DNM1 (0.50) | SMN1; SMN2GPR84SLC22A1CYP3A4TSHR | |
| Malic Acid SCHEMBL4142954 | 0.81 | CA4 (0.54) | CA4SMN1; SMN2MAPTSLC22A6TSHR | |
| Tetrapropylammonium SCHEMBL5874097 | 0.81 | SLC22A1 (0.48) | GPR84SLC22A1CYP3A4TSHRNFKB1 | |
| Cetrimonium SCHEMBL8437300 | 0.81 | DNM1 (0.48) | GPR84MAPTTSHRNPSR1 | |
| Malic Acid SCHEMBL8437259 | 0.81 | DNM1 (0.48) | GPR84MAPTTSHRNPSR1 | |
| Malic Acid SCHEMBL8437740 | 0.81 | DNM1 (0.48) | GPR84MAPTTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |