Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539 | 0.96 | TSHR (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28587072 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Fluoride SCHEMBL923685 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29183872 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5393633 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28878844 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Water SCHEMBL1246621 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Methane SCHEMBL1001960 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL5874477 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL634629 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8301977-A | — | — | None | — | — | JP | disclosed |
| US-9359392-B2 | Dendrimer scaffolds for pharmaceutical use | VICTORIA LINK LIMITED (NZ) | 2016-06-07 | — | — | US | disclosed |
| US-20160145287-A2 | Dendrimer Scaffolds for Pharmaceutical Use | VICTORIA LINK LIMITED (NZ) | 2016-05-26 | — | — | US | disclosed |
| US-20150225439-A1 | Dendrimer Scaffolds for Pharmaceutical Use | VICTORIA LINK LTD (NZ) | 2015-08-13 | — | — | US | disclosed |
| WO-2014038963-A9 | DENDRIMER SCAFFOLDS FOR PHARMACEUTICAL USE | VICTORIA LINK LIMITED (NZ) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014038963-A1 | DENDRIMER SCAFFOLDS FOR PHARMACEUTICAL USE | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2014-03-13 | — | — | WO | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-6899996-B2 | Hydrophilic water swelling particles in nonaqeuos solvent; lithography printing plates | EASTMAN KODAK COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| US-6838226-B2 | A supported aqueous-based imaging layer having overcoating of non-aqueous inverse emulsion of highly hydrophilic, water-swellable microgel particles dispersed in a water-immiscible solvent; durability; lithographic printing plates | EASTMAN KODAK COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| WO-2004104706-A1 | IMAGING MEMBER WITH MICROGEL PROTECTIVE LAYER | EASTMAN KODAK COMPANY (US) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004104705-A1 | PREPARING IMAGING MEMBER WITH MICROGEL PROTECTIVE LAYER | EASTMAN KODAK COMPANY (US) | 2004-12-02 | — | — | WO | disclosed |
| US-20040234890-A1 | Hydrophilic water swelling particles in nonaqeuos solvent; lithography printing plates | EASTMAN KODAK COMPANY | 2004-11-25 | — | — | US | disclosed |
| US-20040234891-A1 | A supported aqueous-based imaging layer having overcoating of non-aqueous inverse emulsion of highly hydrophilic, water-swellable microgel particles dispersed in a water-immiscible solvent; durability; lithographic printing plates | EASTMAN KODAK COMPANY | 2004-11-25 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0608582-B1 | Pyrrolinone dyes and photographic materials containing the same | EASTMAN KODAK CO (US) | 1999-03-10 | — | — | EP | disclosed |
| JP-H08301977-A | PRODUCTION OF COMPOUND CONTAINING CARBOXYL GROUP AND ETHYLENICALLY UNSATURATED GROUP | TOAGOSEI CO LTD | 1996-11-19 | — | — | JP | disclosed |
| US-5283165-A | Solid particular filter dye dispersion in photography | EASTMAN KODAK COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225439-A1 | Dendrimer Scaffolds for Pharmaceutical Use | CD38, ADCYAP1R1, PIGO | TSHR 4706/4885MAPK1 4765/4885MEN1 1286/4885 |
| US-20160145287-A2 | Dendrimer Scaffolds for Pharmaceutical Use | CD38, ADCYAP1R1, PIGO | TSHR 4706/4885MAPK1 4765/4885MEN1 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.