Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539 | 0.96 | TSHR (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28878844 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Fluoride SCHEMBL923685 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29183872 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Methane SCHEMBL1001960 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL5874477 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Water SCHEMBL1246621 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL5874693 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5393633 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL28587072 | 0.93 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987762-A | Superoxide dismutase detection kit | 山东博科生物产业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116135809-A | High-strength concrete additive and preparation method thereof | 深圳场道工程有限公司 | 2023-05-19 | — | — | CN | claimed |
| US-11560497-B2 | Adhesive sheet | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-01-24 | — | — | US | claimed |
| CN-108452303-A | It is a kind of to carry double medicine nanometer formulations and preparation method thereof | 中国药科大学 | 2018-08-28 | — | — | CN | claimed |
| US-20180214481-A1 | READY TO USE SURFACE DISINFECTANT | SPECTRA SHIELD TECHNOLOGIES, LLC (US) | 2018-08-02 | — | — | US | claimed |
| CN-108315327-A | Nucleic acid preservation liquid and preparation method thereof, the method for preserving nucleic acid using the preservation liquid | 杭州百殷生物科技有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-104795536-B | A kind of liquid phase synthesis B3+, La3+Orthohormbic structure of adulterating fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104795539-B | A kind of liquid phase synthesis Cu2+,Fe3+Sheet of adulterating fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104916818-B | A kind of liquid phase synthesis Al3+,Y3+Adulterate cubic structure fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-08-29 | — | — | CN | claimed |
| CN-104909393-B | A kind of liquid phase synthesis fluorination bismuth anode material for lithium-ion batteries and preparation method thereof | 宁波大学 | 2017-07-25 | — | — | CN | claimed |
| WO-2005054376-A1 | CONCENTRATED AQUEOUS COMPOSITIONS OF DYESTUFFS | CLARIANT INTERNATIONAL LTD (CH) | 2005-06-16 | — | — | WO | claimed |
| EP-1139979-A1 | SELF-WARMING HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2001-10-10 | — | — | EP | claimed |
| US-6274128-B1 | FOR SHAMPOOING AND CONDITIONING HAIR | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2001-08-14 | — | — | US | claimed |
| WO-2000038621-A1 | SELF-WARMING HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2000-07-06 | — | — | WO | claimed |
| US-5143518-A | Fatty Acid Soap, Silicone, Cationic Surfactant, Base, Cationic Polymer | L'OREAL (FR) | 1992-09-01 | — | — | US | claimed |
| US-4943430-A | HAIR DYES, CATIONIC POLYMERS | LEVER BROTHERS COMPANY (US) | 1990-07-24 | — | — | US | claimed |
| CN-86101993-B | Hot air leveling soldering flux and preparation method thereof | 华北计算技术研究所 | 1988-10-05 | — | — | CN | claimed |
| CN-86101993-A | Hot air leveling-up scaling powder and compound method | — | 1987-10-07 | — | — | CN | claimed |
| US-4512913-A | BY REACTING GROUP II WATER SOLUBLE METAL SALT WITH ALUMINUM CHLOROHYDRATE COMPLEX | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1985-04-23 | — | — | US | claimed |
| US-3964500-A | Lusterizing shampoo containing a polysiloxane and a hair-bodying agent | LEVER BROTHERS COMPANY (US) | 1976-06-22 | — | — | US | claimed |