Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL8029015 | 0.98 | GPR84 (0.52) | BBOX1AKR1B1GPR84PPARGPPARD | |
| Sebacic Acid SCHEMBL5874757 | 0.98 | GPR84 (0.52) | BBOX1AKR1B1GPR84PPARGPPARD | |
| Tetrylammonium SCHEMBL5875099 | 0.96 | BBOX1 (0.50) | BBOX1AKR1B1GPR84PPARGPPARD | |
| Adipic Acid SCHEMBL5874733 | 0.91 | BBOX1 (0.58) | BBOX1FABP3CA1 | |
| Adipic Acid SCHEMBL8028982 | 0.89 | BBOX1 (0.56) | BBOX1FABP3CA1 | |
| Azelaic Acid SCHEMBL8778169 | 0.89 | BBOX1 (0.56) | BBOX1FABP3CA1 | |
| Sebacic Acid SCHEMBL5874751 | 0.89 | BBOX1 (0.56) | BBOX1FABP3CA1 | |
| Adipic Acid SCHEMBL5874738 | 0.89 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL8538097 | 0.89 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Azelaic Acid SCHEMBL8029012 | 0.86 | BBOX1 (0.54) | BBOX1FABP3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115939421-A | Zirconia-stabilized solid oxide battery fuel electrode material and preparation method and application thereof | 中国科学技术大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-109286018-B | Preparation method of ultrathin two-dimensional carbon sheet | 中国科学院兰州化学物理研究所 | 2021-12-31 | — | — | CN | disclosed |
| CN-113087115-A | Method for removing heavy metal complex in wastewater | 广东工业大学 | 2021-07-09 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0684619-B1 | Ion-conductive polymer electrolyte and electrolytic capacitor using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5733661-A | METAL OXIDE CONTAINING IONS OF AN ORGANIC CARBOXYLIC ACID SALT AND/OR IONS OF AN INORGANIC OXOACID SALT | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0227433-B1 | ELECTROLYTE SOLUTION OF QUATERNARY AMMONIUM SALT FOR ELECTROLYTIC CAPACITOR | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0391333-A2 | Electrolyte for driving electrolytic capacitors and capacitor using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
| US-4715976-A | QUATERNARY AMMONIUM SALT OF CARBOXYLIC ACID IN APROTIC SOLVENT | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0227433-A2 | Electrolyte solution of quaternary ammonium salt for electrolytic capacitor | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4255553-A | COMPRISING A COMPOUND HAVING AT LEAST TWO EPOXY GROUPS, A POLYESTER OR ACRYLIC RESIN, AND A QUARTERNARY AMMONIUM CARBOXYLATE AS CATALYST | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |