Glutarate

Glutarate

SCHEMBL5874790

CC(O)N(C(C)O)C(C)O.O=C(O)CCCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.55
TSHR P16473 6/20 0.50
LMNA P02545 2/20 0.48
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
AKR1B1 P15121 1/20 0.44
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 6/20 0.42
PPARA Q07869 6/20 0.42
HDAC11 Q96DB2 5/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL5875295 0.95 LMNA (0.55) SLC22A6TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL5875431 0.93 TSHR (0.57) SLC22A6TSHRLMNANFKB1PMP22
Succinic Acid SCHEMBL5874469 0.90 EGLN1 (0.50) LMNAALDH1A1
Valeric Acid SCHEMBL5874657 0.89 AKR1B1 (0.56) SLC22A6TSHRLMNAAKR1B1GPR84
Hexanoate SCHEMBL5874551 0.87 AKR1B1 (0.67) SLC22A6TSHRLMNAAKR1B1GPR84
Octanoic Acid SCHEMBL5874222 0.85 GPR84 (0.68) SLC22A6TSHRLMNAAKR1B1GPR84
Heptanoate SCHEMBL5874729 0.85 GPR84 (0.68) SLC22A6TSHRLMNAAKR1B1GPR84
Stearic Acid SCHEMBL919564 0.85 GPR84 (0.68) SLC22A6TSHRLMNAAKR1B1GPR84
Behenic Acid SCHEMBL15973560 0.85 GPR84 (0.68) SLC22A6TSHRLMNAAKR1B1GPR84
Dodecanoate SCHEMBL3470114 0.85 GPR84 (0.68) SLC22A6TSHRLMNAAKR1B1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed