Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.68 |
| ▸ | PPARG | P37231 | 7/20 | 0.68 |
| ▸ | PPARD | Q03181 | 7/20 | 0.68 |
| ▸ | PPARA | Q07869 | 7/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | FABP4 | P15090 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL5874388 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL3470114 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL5874222 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL5874623 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL3469991 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL5874729 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL15973560 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL5712837 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL5874551 | 0.98 | AKR1B1 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| Valeric Acid SCHEMBL5874657 | 0.92 | AKR1B1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8040827-A | — | — | None | — | — | JP | disclosed |
| US-20240091109-A1 | COMPOSITION COMPRISING POLYMERS OF NATURAL ORIGIN AND HAVING PROPERTIES FOR THICKENING POLAR MEDIA | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2024-03-21 | — | — | US | disclosed |
| US-20240091150-A1 | PHARMACEUTICAL COMPOSITION COMPRISING, AS THICKENING AGENT, A COMPOSITION HAVING POLAR MEDIA THICKENING PROPERTIES | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2024-03-21 | — | — | US | disclosed |
| EP-4073170-B1 | PROCESS FOR PREPARING AN INVERSE LATEX FOR COSMETIC COMPOSITION COMBINING A PARTICULAR SEQUESTERING AGENT AND A POLYELECTROLYTE COMPRISING A WEAK ACID FUNCTION | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2024-02-21 | — | — | EP | disclosed |
| US-20240024486-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING A POLYMER IN THE FORM OF A PULVERULENT SOLID AS THICKENING AGENT | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2024-01-25 | — | — | US | disclosed |
| US-20240026078-A1 | Polymer taking the form of a pulverulent solid and having properties for thickening polar media | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2024-01-25 | — | — | US | disclosed |
| EP-3474954-B1 | METHOD FOR OBTAINING A DIGLYCOSIDE-ENRICHED ARMERIA MARITIMA EXTRACT, AND USE THEREOF IN COSMETICS | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2023-11-29 | — | — | EP | disclosed |
| EP-4274417-A1 | PHYTOSANITARY COMPOSITION COMPRISING, AS THICKENING AGENT, A COMPOSITION HAVING POLAR MEDIA THICKENING PROPERTIES | Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) | 2023-11-15 | — | — | EP | disclosed |
| EP-4274859-A1 | COMPOSITION COMPRISING POLYMERS OF NATURAL ORIGIN AND HAVING PROPERTIES FOR THICKENING POLAR MEDIA | Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) | 2023-11-15 | — | — | EP | disclosed |
| EP-4274549-A1 | PHARMACEUTICAL COMPOSITION COMPRISING, AS THICKENING AGENT, A COMPOSITION HAVING POLAR MEDIA THICKENING PROPERTIES | Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) | 2023-11-15 | — | — | EP | disclosed |
| JP-H0840827-A | GEL CLEANSING AGENT | POLA CHEM IND INC | 1996-02-13 | — | — | JP | disclosed |
| US-5294438-A | Water insoluble thermoplastic elastomer and emollient oils; skin sensitivity | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0356196-B1 | Cosmetic preparation | DENTO MED IND INC (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5039516-A | Containing homopolymers of 2-hydroxyethyl methacrylate | DENTO-MED INDUSTRIES, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4917886-A | Novel topically administrable pharmaceutical compositions | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4897214-A | Skin cleaning preparations containing a HLB 10-19 non-ionic emulsifier and a thickening agent | CRINOS INDUSTRIA FARMACOBIOLOGICA SPA. (IT) | 1990-01-30 | — | — | US | disclosed |
| US-4883659-A | AMMONIUM SALT OF FATTY ACID, POLYHYDROXYETHYL METHACRYLATE, SOLVENTS | DENTO-MED INDUSTRIES, INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4774016-A | POLYOXYETHYLENE GLYCOLS AND DERIVATIVES | CRINOS INDUSTRIA FARMACOBIOLOGICA SPA (IT) | 1988-09-27 | — | — | US | disclosed |
| EP-0115888-B1 | PREPARATION WITHOUT DETERGENT INGREDIENTS FOR THE HYGIENE AND THE CLEANING OF SKIN SCALP AND HAIR | Crinos Industria Farmacobiologica S.p.A. (IT) | 1988-04-20 | — | — | EP | disclosed |
| EP-0115888-A1 | Preparation without detergent ingredients for the hygiene and the cleaning of skin scalp and hair | Crinos Industria Farmacobiologica S.p.A. (IT) | 1984-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240091109-A1 | COMPOSITION COMPRISING POLYMERS OF NATURAL ORIGIN AND HAVING PROPERTIES FOR THICKENING POLAR MEDIA | PHOSPHO1, GRIA1, GRM7 | GPR84 113/4885PPARG 60/4885PPARD 1007/4885 |
| US-20240026078-A1 | Polymer taking the form of a pulverulent solid and having properties for thickening polar media | PGAM1, GLUL, SGTA | GPR84 1138/4885PPARG 179/4885PPARD 1486/4885 |
| US-20240024486-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING A POLYMER IN THE FORM OF A PULVERULENT SOLID AS THICKENING AGENT | PGA5, SGTA, GYPA | GPR84 1414/4885PPARG 53/4885PPARD 821/4885 |
| US-20240091150-A1 | PHARMACEUTICAL COMPOSITION COMPRISING, AS THICKENING AGENT, A COMPOSITION HAVING POLAR MEDIA THICKENING PROPERTIES | PHOSPHO1, GYPA, SGTA | GPR84 925/4885PPARG 238/4885PPARD 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.