Quinoline

Quinoline

SCHEMBL5874797

O=C(O)CCCC(=O)O.c1ccc2ncccc2c1.c1ccc2ncccc2c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
HTT P42858 3/20 0.52
CYSLTR2 Q9NS75 4/20 0.50
CYSLTR1 Q9Y271 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
PRNP P04156 1/20 0.47
MAPK10 P53779 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
ALOX15 P16050 1/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.44
PABPC1 P11940 1/20 0.44
POLB P06746 1/20 0.44
HDAC3 O15379 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
HDAC4 P56524 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL5874806 1.00 ALDH1A1 (0.61) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Adipic Acid SCHEMBL5875328 0.96 ALDH1A1 (0.61) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Adipic Acid SCHEMBL5875340 0.96 ALDH1A1 (0.61) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Adipic Acid SCHEMBL28641209 0.96 ALDH1A1 (0.61) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Sebacic Acid SCHEMBL5875076 0.95 ALDH1A1 (0.59) ALDH1A1HTTCYSLTR2CYSLTR1PRNP
Sebacic Acid SCHEMBL5875085 0.95 ALDH1A1 (0.59) ALDH1A1HTTCYSLTR2CYSLTR1PRNP
Quinoline SCHEMBL4733766 0.93 ALDH1A1 (0.65) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Quinoline SCHEMBL5874815 0.93 ALDH1A1 (0.65) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Quinoline SCHEMBL5874561 0.90 ALDH1A1 (0.53) ALDH1A1HTTCYSLTR2CYSLTR1SMN1; SMN2
Quinoline SCHEMBL5875240 0.89 ALDH1A1 (0.52) ALDH1A1ALOX15TSHRHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed