Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1131781 | 0.94 | KDM4E (0.53) | KDM4EALDH1A1HPGDCA12CA9 | |
| Salicylic Acid SCHEMBL6653091 | 0.94 | KDM4E (0.53) | KDM4EALDH1A1HPGDCA12CA9 | |
| Salicylic Acid SCHEMBL14675456 | 0.94 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDCA12CA9 | |
| Salicylic Acid SCHEMBL5874944 | 0.90 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDCA12CA9 | |
| Phthalic Acid SCHEMBL5875359 | 0.90 | ALDH1A1 (0.55) | KDM4EALDH1A1CA12CA9POLB | |
| Phthalic Acid SCHEMBL5875365 | 0.90 | ALDH1A1 (0.55) | KDM4EALDH1A1CA12CA9POLB | |
| Salicylic Acid SCHEMBL8621859 | 0.88 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDCA12CA9 | |
| Salicylic Acid SCHEMBL294304 | 0.88 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDCA12CA9 | |
| Salicylic Acid SCHEMBL28366261 | 0.86 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDCA12CA9 | |
| Hexadecane SCHEMBL28225619 | 0.86 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |