Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1131781 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL5874800 | 0.94 | KDM4E (0.60) | KDM4EALDH1A1HPGDCA12CA1 | |
| Phthalic Acid SCHEMBL1131705 | 0.91 | ALDH1A1 (0.50) | KDM4EALDH1A1CA12CA9POLB | |
| Salicylic Acid SCHEMBL5874177 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL19717848 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL10788832 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL15847 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL1904685 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL15717117 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 | |
| Salicylic Acid SCHEMBL5313430 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523583-B2 | Catholyte for the coulometric Karl Fischer titration of water | RIEDEL DE HAEN AG (DE) | 2004-01-14 | — | — | EP | disclosed |
| EP-0523583-B1 | Catholyte for the coulometric Karl Fischer titration of water | RIEDEL DE HAEN AG (DE) | 1997-09-10 | — | — | EP | disclosed |
| US-5292413-A | Catholyte for the Karl Fischer coulometric water determination | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| EP-0523583-A1 | Catholyte for the coulometric Karl Fischer titration of water | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1993-01-20 | — | — | EP | disclosed |