Malonic Acid

Malonic Acid

SCHEMBL5874801

CNC.O=C(O)CC(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.75
SRR Q9GZT4 1/20 0.75
FFAR3 O14843 3/20 0.47
EGLN1 Q9GZT9 3/20 0.41
KDM4E B2RXH2 3/20 0.41
KDM5C P41229 2/20 0.41
PHF8 Q9UPP1 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
LMNA P02545 3/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
TSHR P16473 4/20 0.38
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
SLC15A2 Q16348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL5874793 1.00 LDHA (0.75) LDHASRRFFAR3EGLN1KDM4E
Malonic Acid SCHEMBL782125 0.87
Malonic Acid SCHEMBL3608474 0.87
Malonic Acid SCHEMBL336 0.87
Malonic Acid SCHEMBL1332554 0.87
Malonic Acid SCHEMBL23831 0.87 LDHA (1.00) LDHASRRFFAR3EGLN1KDM4E
Malonic Acid SCHEMBL3358611 0.87
Malonic Acid SCHEMBL1332405 0.87
Malonic Acid SCHEMBL1332587 0.87
Malonic Acid SCHEMBL15711068 0.87 LDHA (0.56) LDHASRRFFAR3EGLN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228449-A1 METHOD FOR PREPARING TERTIARY AMINE WITH SECONDARY AMINE AS RAW MATERIAL ZHEJIANG XINHUA CHEMICAL CO., LTD (CN) 2024-07-11 US disclosed
EP-4324820-A1 METHOD FOR PREPARING TERTIARY AMINE BY USING SECONDARY AMINE AS RAW MATERIAL Zhejiang Xinhua Chemical Co., Ltd. (CN) 2024-02-21 EP disclosed
CN-116478046-A Method for preparing tertiary amine by taking secondary amine as raw material 浙江新化化工股份有限公司 2023-07-25 CN disclosed
WO-2023134439-A1 METHOD FOR PREPARING TERTIARY AMINE BY USING SECONDARY AMINE AS RAW MATERIAL 浙江新化化工股份有限公司 2023-07-20 WO disclosed
CN-109475574-A Crosslinkable coating compositions formulated with dormant carbamate initiators 海名斯精细化工公司 2019-03-15 CN disclosed
US-20160250722-A1 HIGH-CONCENTRATION FLUX FOR BEING SPRAYED ON PREFORM GUANGZHOU SOLDERWELL ADVANCED MATERIALS CO., LTD. (CN) 2016-09-01 US disclosed
CN-103537822-A High-concentration scaling powder for pre-forming soldering lug spraying GUANGZHOU SOLDERWELL ADVANCED MATERIALS CO LTD 2014-01-29 CN disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed
US-4421914-A IMMUNE FUNCTION REGULATORS TEIJIN LIMITED (JP) 1983-12-20 US disclosed
EP-0049902-A2 Novel thiazolo(3,2-a)pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228449-A1 METHOD FOR PREPARING TERTIARY AMINE WITH SECONDARY AMINE AS RAW MATERIAL OTC, AOC1, ODC1 LDHA 217/4885SRR 1490/4885FFAR3 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.