Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | KDM5A | P29375 | 4/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5874864 | 1.00 | CA12 (0.54) | CA12CA1CA9KDM5APHF8 | |
| Acetic Acid SCHEMBL692128 | 0.92 | CA12 (0.52) | CA12CA1CA9KDM5APHF8 | |
| Oxalic Acid SCHEMBL5874878 | 0.92 | CA12 (0.52) | CA12CA1CA9KDM5APHF8 | |
| Acetic Acid SCHEMBL27778890 | 0.92 | CA12 (0.52) | CA12CA1CA9KDM5APHF8 | |
| Oxalic Acid SCHEMBL5844731 | 0.92 | CA12 (0.52) | CA12CA1CA9KDM5APHF8 | |
| Hydrogen Peroxide SCHEMBL137833 | 0.91 | KDM5A (0.48) | CA12CA1CA9KDM5APHF8 | |
| Hydrogen Peroxide SCHEMBL137835 | 0.91 | KDM5A (0.48) | CA12CA1CA9KDM5APHF8 | |
| Bicarbonate SCHEMBL1131246 | 0.90 | KDM5A (0.47) | CA12CA1CA9KDM5APHF8 | |
| Bicarbonate SCHEMBL1132307 | 0.90 | KDM5A (0.47) | CA12CA1CA9KDM5APHF8 | |
| Bicarbonate SCHEMBL28356729 | 0.89 | KDM5A (0.56) | KDM5APHF8KDM4CAKR1B1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501779-A | Method for selectively removing benzyl, allyl and propargyl protecting groups initiated by visible light or near visible light | 云南大学 | 2021-10-15 | — | — | CN | claimed |
| CN-116134068-A | Polymerization process | 牛津大学科技创新有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |