Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874870 | 1.00 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Pimelic Acid SCHEMBL27899346 | 0.97 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL5874987 | 0.97 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Trimethylammonium SCHEMBL11145139 | 0.97 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL5874992 | 0.97 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Azelaic Acid SCHEMBL17765551 | 0.97 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Glutarate SCHEMBL5874412 | 0.93 | SLC22A6 (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Glutarate SCHEMBL5874406 | 0.93 | SLC22A6 (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Hexanoate SCHEMBL3414358 | 0.89 | AKR1B1 (0.84) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Adipic Acid SCHEMBL28248680 | 0.89 | LMNA (0.58) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9953767-B2 | Conductive polymer dispersion liquid, a conductive polymer, and use thereof | TAYCA CORPORATION (JP) | 2018-04-24 | — | — | US | disclosed |
| CN-107848947-A | Fluorochemical, living polymerization initiator, fluoropolymer, the manufacture method of fluoropolymer and anti-corrosion agent composition | DIC株式会社 | 2018-03-27 | — | — | CN | disclosed |
| CN-105348667-B | Electroconductive polymer dispersion liquid, electroconductive polymer and application thereof | 帝化株式会社 | 2018-01-23 | — | — | CN | disclosed |
| US-20170025227-A1 | CONDUCTIVE POLYMER DISPERSION LIQUID, A CONDUCTIVE POLYMER, AND USE THEREOF | TAYCA CORPORATION (JP) | 2017-01-26 | — | — | US | disclosed |
| US-9460860-B2 | Dispersion of electrically conductive polymer, and electrically conductive polymer and use thereof | TAYCA CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| CN-103748164-B | Conductive polymer dispersion, conductive polymer, and use thereof | 帝化株式会社 | 2016-09-14 | — | — | CN | disclosed |
| CN-105348667-A | Dispersion of electrically conductive polymer, and electrically conductive polymer and use thereof | TAYCA CORP | 2016-02-24 | — | — | CN | disclosed |
| CN-104549371-A | Catalyst of preparing isophorone by condensation of acetone and preparation method of catalyst | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-102791820-B | Adhesive composition, use thereof, connection structure of circuit member, and method for producing connection structure of circuit member | HITACHI CHEMICAL CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-20140211374-A1 | DISPERSION OF ELECTRICALLY CONDUCTIVE POLYMER, AND ELECTRICALLY CONDUCTIVE POLYMER AND USE THEREOF | TAYCA CORPORATION (JP) | 2014-07-31 | — | — | US | disclosed |
| CN-103748164-A | Conductive polymer dispersion, conductive polymer, and use thereof | TAYCA CORP | 2014-04-23 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| CN-1161398-C | Process for preparing spinning polyamide 6 | 因万塔-费希尔股份公司 | 2004-08-11 | — | — | CN | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1091778-C | Weather-resistant polyamides and method of their production | INVENTA AG (CH) | 2002-10-02 | — | — | CN | disclosed |
| CN-1259533-A | Process for preparing spinning polyamide 6 | INVENTIO FISHER CO LTD (CH) | 2000-07-12 | — | — | CN | disclosed |
| CN-1173509-A | Weather-resistant polyamides and method of their production | INVENTA AG (CH) | 1998-02-18 | — | — | CN | disclosed |