SCHEMBL5875401

SCHEMBL5875401

CC(N)O.O=S(=O)(O)c1ccccc1

nearest known ligand 0.70

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
CYP2D6 P10635 2/20 0.48
POLB P06746 2/20 0.48
ALDH1A1 P00352 5/20 0.46
NT5E P21589 1/20 0.46
TDP1 Q9NUW8 3/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPK1 P28482 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylamine SCHEMBL25405525 0.93 TSHR (0.73) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
Isopropyl Alcohol SCHEMBL5735328 0.91 TSHR (0.76) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
SCHEMBL16046756 0.89 TSHR (0.73) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
Alanine SCHEMBL10626231 0.88 TSHR (0.64) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
Alanine SCHEMBL10627958 0.88 TSHR (0.64) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
SCHEMBL28902110 0.87 TSHR (0.70) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
Methylamine SCHEMBL5875184 0.86 TSHR (0.84) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
Lactic Acid SCHEMBL232168 0.85 TSHR (0.67) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
SCHEMBL16045501 0.85 TSHR (0.67) TSHRSMN1; SMN2CYP2D6POLBALDH1A1
SCHEMBL27872661 0.84 TSHR (0.73) TSHRSMN1; SMN2CYP2D6POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed