SCHEMBL5875604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5875673	0.87	PSEN1 (0.47)	SMN1; SMN2ALDH1A1CCNT1CDK1CDK4
	SCHEMBL5875607	0.82	SIGMAR1 (0.45)	PARP1SMN1; SMN2ALDH1A1CCNT1CDK1
	SCHEMBL5875576	0.81	PSEN1 (0.35)	PARP1SMN1; SMN2ALDH1A1CCNT1CDK1
	SCHEMBL5875546	0.81	PSEN1 (0.44)	PARP1SMN1; SMN2ALDH1A1CCNT1CDK1
	SCHEMBL5875830	0.80	PSEN1 (0.44)	SMN1; SMN2ALDH1A1CCNT1CDK1CDK4
	SCHEMBL5875677	0.79	PSEN1 (0.46)	PARP1SMN1; SMN2CCNE1CDK2CDK5
	SCHEMBL5875579	0.78	PARP1 (0.49)	PARP1SMN1; SMN2ALDH1A1SIGMAR1KMT2A
	SCHEMBL5875670	0.78	CA2 (0.38)	ALDH1A1CCNE1CDK2CDK5
	SCHEMBL5875539	0.78	PSEN1 (0.46)	CCNE1CDK2CDK5
	SCHEMBL5875760	0.72	PSEN1 (0.38)	PARP1SMN1; SMN2ALDH1A1CCNT1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.