Crotonic Acid

Crotonic Acid

SCHEMBL5875704

C=CN1CCCC1=O.CC=CC(=O)O

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.38
INMT O95050 3/20 0.34
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonic Acid SCHEMBL9316662 1.00 BLM (0.38) BLMINMTBRD4BRD2LMNA
Maleic Acid SCHEMBL6356254 0.90 BLM (0.45) BLMINMTBRD4BRD2LMNA
Fumaric Acid SCHEMBL8972811 0.90 BLM (0.45) BLMINMTBRD4BRD2LMNA
Sorbic Acid SCHEMBL27944952 0.89 BLM (0.36) BLMINMTBRD4BRD2LMNA
Acetic Acid SCHEMBL887070 0.84 BRD4 (0.39) BLMBRD4BRD2LMNAALDH1A1
Acrylic Acid SCHEMBL1405902 0.84 LMNA (0.39) BLMINMTBRD4BRD2LMNA
Bicarbonate SCHEMBL28233410 0.84 LMNA (0.39) BLMINMTBRD4BRD2LMNA
SCHEMBL28145114 0.84 BRD4 (0.41) BRD4BRD2LMNACA12CA1
Hydrogen Peroxide SCHEMBL610401 0.84 BRD4 (0.39) BLMBRD4BRD2LMNAALDH1A1
Hydrogen Peroxide SCHEMBL2561887 0.84 BRD4 (0.39) BLMBRD4BRD2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101993687-B Water-soluble anti-free radical stabilizer and preparation method thereof CHINA PETROLEUM & CHEMICAL 2013-02-06 CN claimed
CN-101993687-A Water-soluble anti-free radical stabilizer and preparation method thereof CHINA PETROLEUM & CHEMICAL 2011-03-30 CN claimed
CN-101993687-B Water-soluble anti-free radical stabilizer and preparation method thereof CHINA PETROLEUM & CHEMICAL 2013-02-06 CN disclosed
CN-101993687-A Water-soluble anti-free radical stabilizer and preparation method thereof CHINA PETROLEUM & CHEMICAL 2011-03-30 CN disclosed
US-7008990-B2 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2006-03-07 US disclosed
US-6815498-B2 BLOCK POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-11-09 US disclosed
US-6710024-B2 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2004-03-23 US disclosed
US-20040034182-A1 Method for the production of a polymerisation reaction product BASF AKTIENGESELLSCHAFT (DE) 2004-02-19 US disclosed
US-20040014872-A1 Bonding agent composition containing solid matter, with radically polymerised block copolymers BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-20030170306-A1 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2003-09-11 US disclosed
US-20030109414-A1 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2003-06-12 US disclosed
US-20030018137-A1 Method for producing a polymeric conversion product BASF AKTIENGESELLSCHAFT (DE) 2003-01-23 US disclosed
US-5331067-A Acrylic polymers containing trimethylsiloxy groups PERMEABLE TECHNOLOGIES, INC. (US) 1994-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030170306-A1 Use of polymeric reaction product OXSR1, OGFR, CBR1 BLM 2198/4885INMT 2731/4885BRD4 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.