SCHEMBL5875732

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5875803	0.83	CA2 (0.42)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5875727	0.79	SLC8A1 (0.38)	HTTL3MBTL1SLC8A1HDAC1
	SCHEMBL27646959	0.78	SMN1; SMN2 (0.41)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5875708	0.78	SMN1; SMN2 (0.46)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL6193695	0.77	POLB (0.39)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5875819	0.76	SMN1; SMN2 (0.45)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5835893	0.73	ALDH1A1 (0.46)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5875833	0.71	PSEN1 (0.40)	ALDH1A1MAPTHTTTDP1SMN1; SMN2
	SCHEMBL6198202	0.70	SMN1; SMN2 (0.46)	POLBALDH1A1MAPTTHRBHTT
	SCHEMBL5132531	0.70	MEN1 (0.42)	NOS1CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.