SCHEMBL587674

SCHEMBL587674

[SiH3]O[SiH2]C(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.36
TSHR P16473 2/20 0.36
F2 P00734 1/20 0.36
HTR2A P28223 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP2D6 P10635 2/20 0.32
SRC P12931 1/20 0.32
KMT2A Q03164 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRA1A P35348 1/20 0.31
RGS12 O14924 1/20 0.31
GLA P06280 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514830 0.82 DPP4 (0.31) DPP4TSHRF2
SCHEMBL433140 0.79 DPP4 (0.39) DPP4TSHRF2HTR2ATAAR1
SCHEMBL8837406 0.78 TSHR (0.46) DPP4TSHRF2HTR2ATAAR1
SCHEMBL3157665 0.76 CYP2D6 (0.38) TSHRHTR2ATAAR1CYP2D6KMT2A
SCHEMBL704150 0.75 KMT2A (0.40) DPP4TSHRF2HTR2ATAAR1
SCHEMBL707823 0.75 SLC6A4 (0.37) DPP4TSHRF2HTR2ACYP2D6
SCHEMBL17865441 0.73 DPP4 (0.35) DPP4TSHRF2HTR2ATAAR1
SCHEMBL703093 0.73 SCN4A (0.38) DPP4TSHRF2HTR2ATAAR1
SCHEMBL876939 0.72 CYP2C19 (0.35) DPP4TSHRF2KMT2ACYP3A4
SCHEMBL11766458 0.72 ACP3 (0.33) DPP4TSHRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1800660-B2 Cosmetic ingredient comprising at least one cationic poly(vinyllactam), at least one specific cross-linked cationic polymer and at least one non-volatile silicon OREAL (FR) 2019-03-27 EP claimed
EP-1800659-B1 Cosmetic composition comprising at least one cationic polyvinyllactam, at least one fatty alcohol and at least one polyol, method for treatment of keratin fibres and use L'ORÉAL (FR) 2017-09-27 EP claimed
EP-1800658-B2 Cosmetic composition comprising at least one cationic polyvinyllactam, at least one fatty alcohol and at least one aminosilicone, cosmetic treatment method and use ORÉAL L (FR) 2016-08-31 EP claimed
EP-1800660-B1 Cosmetic ingredient comprising at least one cationic poly(vinyllactam), at least one specific cross-linked cationic polymer and at least one non-volatile silicon ORÉAL L (FR) 2016-02-17 EP claimed
EP-1800658-B1 Cosmetic composition comprising at least one cationic polyvinyllactam, at least one fatty alcohol and at least one aminosilicone, cosmetic treatment method and use OREAL (FR) 2012-08-22 EP claimed
EP-1800658-A1 Cosmetic composition comprising at least one cationic polyvinyllactam, at least one fatty alcohol and at least one aminosilicone, cosmetic treatment method and use L'Oréal (FR) 2007-06-27 EP claimed
EP-1800659-A1 Cosmetic composition comprising at least one cationic polyvinyllactam, at least one fatty alcohol and at least one polyol, method for treatment of keratin fibres and use L'Oréal (FR) 2007-06-27 EP claimed
EP-1800660-A1 Cosmetic ingredient comprising at least one cationic poly(vinyllactam), at least one specific cross-linked cationic polymer and at least one non-volatile silicon L'Oréal (FR) 2007-06-27 EP claimed
EP-1097956-B1 Polycarbonat resin MITSUBISHI GAS CHEMICAL CO (JP) 2006-04-12 EP claimed
EP-1009366-B1 COSMETIC COMPOSITIONS COMPRISING A POLYOXYALKYLATED AMINATED SILICONE BLOCK POLYMER AND A CONDITIONING AGENT AND THEIR USE OREAL (FR) 2003-03-26 EP claimed
US-4028339-A UTENSILS GENERAL ELECTRIC COMPANY (US) 1977-06-07 US claimed
CN-112652756-B In-situ polymerization protection lithium metal electrode 通用汽车环球科技运作有限责任公司 2024-05-24 CN disclosed
US-11515538-B2 In-situ polymerization to protect lithium metal electrodes GM Global Technology Operations LLC (US) 2022-11-29 US disclosed
CN-114981983-A Thermoelectric conversion structure 株式会社朝日橡胶 2022-08-30 CN disclosed
US-20210111407-A1 IN-SITU POLYMERIZATION TO PROTECT LITHIUM METAL ELECTRODES GM Global Technology Operations LLC (US) 2021-04-15 US disclosed
US-4252932-A STORAGE STABILITY; BY-PRODUCT INHIBITION DOW CORNING CORPORATION (US) 1981-02-24 US disclosed
US-4239674-A ELASTOMERIC SEALANTS, ENCAPSULATING GELS, COATING RESINS DOW CORNING CORPORATION (US) 1980-12-16 US disclosed
US-4231909-A NON-EXUDING DOW CORNING CORPORATION (US) 1980-11-04 US disclosed
US-4198131-A Silicone resin optical devices DOW CORNING CORPORATION (US) 1980-04-15 US disclosed
US-3933678-A Optically clear organosilicon compounds DOW CORNING CORPORATION (US) 1976-01-20 US disclosed