Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587891 | 0.79 | ALDH1A1 (0.41) | CYP2D6CYP3A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL8142566 | 0.78 | SLC6A4 (0.40) | CYP2D6CYP3A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL587674 | 0.76 | DPP4 (0.36) | CYP2D6CYP3A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL8837406 | 0.74 | TSHR (0.46) | CYP2D6CYP3A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL8384502 | 0.73 | TAAR1 (0.41) | CYP2D6ADRA2CTSHRTAAR1ALDH1A1 | |
| SCHEMBL28693715 | 0.72 | ALDH1A1 (0.37) | CYP2D6CYP3A4ADRA2CCHRM2ADRA1A | |
| SCHEMBL19973312 | 0.72 | ALDH1A1 (0.44) | CYP2D6CYP3A4CHRM2ADRA1ACYP2C19 | |
| SCHEMBL28670823 | 0.71 | LMNA (0.37) | CYP2D6CYP3A4CHRM2ADRA1ACYP2C19 | |
| SCHEMBL9505903 | 0.70 | TAAR1 (0.38) | CYP2D6ADRA2CTSHRTAAR1ALDH1A1 | |
| SCHEMBL8809690 | 0.70 | HCAR2 (0.37) | CYP2D6ADRA2CTAAR1ALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819776-B1 | AESTHETIC, STABLE CHROMATIC EMULSIONS | AVON PROD INC (US) | 2010-03-03 | — | — | EP | claimed |
| US-4476291-A | Resins containing β-phenylethyl trifunctional siloxy units and method for making | GENERAL ELECTRIC COMPANY (US) | 1984-10-09 | — | — | US | disclosed |