Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878279 | 0.90 | CYP2D6 (0.45) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5877929 | 0.89 | CYP2D6 (0.42) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5877630 | 0.88 | CYP2D6 (0.49) | ABCC1CYP2D6 | |
| SCHEMBL5877473 | 0.87 | CYP2D6 (0.46) | ALDH1A1NPSR1PLA2G1BATG4BLMNA | |
| SCHEMBL5877050 | 0.81 | ABCC1 (0.62) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5877489 | 0.80 | ABCC1 (0.53) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5878320 | 0.80 | ABCC1 (0.62) | ABCC1ALDH1A1NPSR1TDP1L3MBTL1 | |
| SCHEMBL5877881 | 0.78 | ABCC1 (0.53) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5877284 | 0.78 | ATM (0.58) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B | |
| SCHEMBL5878390 | 0.77 | ABCC1 (0.59) | ABCC1ALDH1A1NPSR1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060706-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1216233-A1 | QUINAZOLINONES | MERCK PATENT GmbH (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023364-A1 | QUINAZOLINONES | MERCK PATENT GMBH (DE) | 2001-04-05 | — | — | WO | disclosed |