Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823271 | 0.79 | CA2 (0.30) | CA2 | |
| SCHEMBL6601319 | 0.72 | TSHR (0.37) | TSHRCA2ALDH1A1TDP1 | |
| SCHEMBL20661177 | 0.72 | ALDH1A1 (0.35) | TSHRALDH1A1TP53 | |
| SCHEMBL26619747 | 0.70 | ELANE (0.36) | CA2 | |
| SCHEMBL27330555 | 0.67 | — | — | |
| SCHEMBL4363246 | 0.65 | CA2 (0.44) | TSHRCA2TDP1 | |
| SCHEMBL3067997 | 0.65 | CA2 (0.44) | TSHRCA2TDP1 | |
| SCHEMBL672469 | 0.65 | ALDH1A1 (0.44) | TSHRALDH1A1TP53 | |
| SCHEMBL150679 | 0.65 | ALDH1A1 (0.44) | TSHRALDH1A1TP53 | |
| Trichloroacetic Acid SCHEMBL17652024 | 0.65 | TSHR (0.62) | TSHRCA2ALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103736465-B | A kind of modification waste Crumb rubber for Adsorption of Heavy Metals and preparation method thereof | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-103736465-A | Modified waste rubber powder for absorbing heavy metals and preparation method thereof | UNIV HUAZHONG SCIENCE TECH | 2014-04-23 | — | — | CN | claimed |
| CN-103736465-B | A kind of modification waste Crumb rubber for Adsorption of Heavy Metals and preparation method thereof | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-103736465-A | Modified waste rubber powder for absorbing heavy metals and preparation method thereof | UNIV HUAZHONG SCIENCE TECH | 2014-04-23 | — | — | CN | disclosed |
| US-7084174-B2 | Administration of isovaleryl L-carnitine to stimulate osteoblastic activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-08-01 | — | — | US | disclosed |
| EP-1351676-B1 | USE OF ISOVALERYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND CURE OF OSTEOPOROSIS | SIGMA TAU IND FARMACEUTI (IT) | 2005-08-17 | — | — | EP | disclosed |
| US-20050143458-A1 | Use of isovaleryl L-carnitine for the preparation of a medicament for the prevention and cure of fractures | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-06-30 | — | — | US | disclosed |
| US-6906102-B2 | Use of isovaleryl L-carnitine to increase healing of bone fractures | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-06-14 | — | — | US | disclosed |
| US-20040077718-A1 | Use of isovaleryl l-carnitine for the preparation of a medicament for the prevention and cure of osteoporosis | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-04-22 | — | — | US | disclosed |
| EP-1351676-A1 | USE OF ISOVALERYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND CURE OF OSTEOPOROSIS | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002049639-A1 | USE OF ISOVALERYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND CURE OF OSTEOPOROSIS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-06-27 | — | — | WO | disclosed |