Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930675 | 0.80 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL7182154 | 0.76 | CA1 (0.37) | CA2 | |
| SCHEMBL17267891 | 0.76 | — | — | |
| SCHEMBL144168 | 0.76 | USP2 (0.32) | TSHR | |
| SCHEMBL576147 | 0.76 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1CA2 | |
| SCHEMBL3930282 | 0.75 | ALDH1A1 (0.41) | TSHRTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL18762982 | 0.74 | FAAH (0.31) | — | |
| SCHEMBL28539958 | 0.74 | ATR (0.31) | TSHR | |
| SCHEMBL28232140 | 0.74 | MEN1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL5878321 | 0.72 | TSHR (0.33) | TSHRTDP1ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497354-B2 | Efficient conversion of methane to methanesulfonic acid via trifluoroacetylsulfuric acid | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2025-12-16 | — | — | US | claimed |
| US-20230242477-A1 | EFFICIENT CONVERSION OF METHANE TO METHANESULFONIC ACID VIA TRIFLUOROACETYLSULFURIC ACID | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2023-08-03 | — | — | US | claimed |
| EP-3527573-B9 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2022-07-06 | — | — | EP | claimed |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | GILEAD SCIENCES, INC. (US) | 2021-04-13 | — | — | US | claimed |
| EP-3783001-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2021-02-24 | — | — | EP | claimed |
| EP-3527573-B1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2020-08-12 | — | — | EP | claimed |
| US-20200223866-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES, INC. | 2020-07-16 | — | — | US | claimed |
| CN-110461905-A | Poly- (ether ether ketone) copolymer of block and corresponding synthetic method and product | SOLVAY SPECIALTY POLYMERS IT | 2019-11-15 | — | — | CN | claimed |
| CN-110317212-A | The synthesis of polycyclic carbamoylpyridone compound | 吉利德科学公司 | 2019-10-11 | — | — | CN | claimed |
| EP-3527573-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-08-21 | — | — | EP | claimed |
| CN-103736465-B | A kind of modification waste Crumb rubber for Adsorption of Heavy Metals and preparation method thereof | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-13 | — | — | CN | claimed |
| WO-2015195656-A2 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES ,INC. (US) | 2015-12-23 | — | — | WO | claimed |
| CN-103736465-A | Modified waste rubber powder for absorbing heavy metals and preparation method thereof | UNIV HUAZHONG SCIENCE TECH | 2014-04-23 | — | — | CN | claimed |
| EP-0957109-B1 | Novel processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | AVENTIS PHARMA INC (US) | 2004-05-06 | — | — | EP | claimed |
| EP-0800527-B1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL INC (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0957109-A2 | Novel processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1999-11-17 | — | — | EP | claimed |
| US-5734049-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1998-03-31 | — | — | US | claimed |
| EP-0800527-A1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-15 | — | — | EP | claimed |
| US-5641880-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-24 | — | — | US | claimed |
| WO-1996019492-A1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL, INC. (US) | 1996-06-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223866-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | CPS1, SDHA, DHPS | TSHR 3840/4885TDP1 3399/4885ALDH1A1 883/4885 |
| US-20230242477-A1 | EFFICIENT CONVERSION OF METHANE TO METHANESULFONIC ACID VIA TRIFLUOROACETYLSULFURIC ACID | HAO2, TST, HAGH | TSHR 1530/4885TDP1 3063/4885ALDH1A1 1952/4885 |
| US-12497354-B2 | Efficient conversion of methane to methanesulfonic acid via trifluoroacetylsulfuric acid | HAO2, TST, HAGH | TSHR 1530/4885TDP1 3063/4885ALDH1A1 1952/4885 |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | CPS1, SDHA, DHPS | TSHR 3840/4885TDP1 3399/4885ALDH1A1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.