Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878432 | 0.78 | LMNA (0.49) | ALDH1A1SMN1; SMN2RAB9AQPCTLGLA | |
| SCHEMBL28060400 | 0.74 | LMNA (0.35) | ALDH1A1SMN1; SMN2RAB9AQPCTLGLA | |
| SCHEMBL16328893 | 0.74 | LMNA (0.37) | ALDH1A1SMN1; SMN2RAB9AQPCTLGLA | |
| SCHEMBL11617013 | 0.74 | LMNA (0.38) | ALDH1A1SMN1; SMN2RAB9AGLALMNA | |
| SCHEMBL9467304 | 0.74 | LMNA (0.35) | ALDH1A1SMN1; SMN2RAB9AQPCTLGLA | |
| SCHEMBL16375295 | 0.73 | LMNA (0.43) | ALDH1A1SMN1; SMN2LMNATHRBMEN1 | |
| SCHEMBL28050025 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2RAB9AGLALMNA | |
| Cyclopropane SCHEMBL27295473 | 0.73 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2RAB9AQPCTLGLA | |
| SCHEMBL11615550 | 0.72 | GLA (0.47) | ALDH1A1SMN1; SMN2RAB9AGLALMNA | |
| SCHEMBL5332268 | 0.72 | LMNA (0.67) | ALDH1A1SMN1; SMN2GLALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3928374-A | Nitroimidazole derivatives | JANSSEN PHARMACEUTICA NV | 1975-12-23 | — | — | US | disclosed |