Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101356 | 0.80 | CYP1A2 (0.54) | GAAMGLL | |
| SCHEMBL24785865 | 0.79 | GAA (0.51) | CHRNA7HTR3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5878556 | 0.79 | AGTR2 (0.48) | CHRNA7HTR3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12474666 | 0.77 | CHRNA7 (0.47) | CHRNA7HTR3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12094663 | 0.77 | HTR2C (0.55) | SMN1; SMN2AGTR2NPC1RAB9ACYP3A4 | |
| SCHEMBL154134 | 0.77 | HTR2C (0.55) | SMN1; SMN2AGTR2NPC1RAB9ACYP3A4 | |
| SCHEMBL13739665 | 0.76 | CHRNA7 (0.35) | CHRNA7HTR3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13739663 | 0.76 | CHRNA7 (0.35) | CHRNA7HTR3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL18151944 | 0.75 | ELOVL6 (0.47) | CHRNA7HTR3AALDH1A1KDM4E | |
| SCHEMBL18151912 | 0.75 | ELOVL6 (0.47) | CHRNA7HTR3AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006518367-A | — | — | 2006-08-10 | — | — | JP | claimed |
| US-20060173063-A1 | Exo-(t-butyl 2R(+))-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate, intermediates, and process to prepare and isolate them | PFIZER INC. | 2006-08-03 | — | — | US | claimed |
| EP-1599483-A1 | EXO-(T-BUTYL 2R(+))-2-AMINO-7-AZABICYCLO 2.2.1 HEPTANE- 7-CARBOXYLATE, INTERMEDIATES, AND PROCESS TO PREPARE AND ISOLATE THEM | Pharmacia & Upjohn Company LLC (US) | 2005-11-30 | — | — | EP | claimed |
| WO-2004074292-A1 | EXO-(T-BUTYL 2R(+))-2-AMINO-7-AZABICYCLO[2.2.1]HEPTANE-7-CARBOXYLATE, INTERMEDIATES, AND PROCESS TO PREPARE AND ISOLATE THEM | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-09-02 | — | — | WO | claimed |
| US-20060173063-A1 | Exo-(t-butyl 2R(+))-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate, intermediates, and process to prepare and isolate them | PFIZER INC. | 2006-08-03 | — | — | US | disclosed |
| EP-1599483-A1 | EXO-(T-BUTYL 2R(+))-2-AMINO-7-AZABICYCLO 2.2.1 HEPTANE- 7-CARBOXYLATE, INTERMEDIATES, AND PROCESS TO PREPARE AND ISOLATE THEM | Pharmacia & Upjohn Company LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004074292-A1 | EXO-(T-BUTYL 2R(+))-2-AMINO-7-AZABICYCLO[2.2.1]HEPTANE-7-CARBOXYLATE, INTERMEDIATES, AND PROCESS TO PREPARE AND ISOLATE THEM | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173063-A1 | Exo-(t-butyl 2R(+))-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate, intermediates, and process to prepare and isolate them | EXOC1, EXOC3, EXOC4 | CHRNA7 319/4885HTR3A 1535/4885GAA 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.