Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151912 | 1.00 | ELOVL6 (0.47) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| SCHEMBL18151913 | 0.81 | ELOVL6 (0.52) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| SCHEMBL2990830 | 0.80 | ELOVL6 (0.48) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| SCHEMBL3456856 | 0.79 | ALDH1A1 (0.44) | L3MBTL3L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL14172576 | 0.79 | CHRNB2 (0.56) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| SCHEMBL21162194 | 0.79 | ELOVL6 (0.53) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL27153138 | 0.77 | CHRNB2 (0.54) | ELOVL6L3MBTL3L3MBTL1ACHEALDH1A1 | |
| SCHEMBL23021253 | 0.76 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL5878652 | 0.75 | CHRNA7 (0.50) | ALDH1A1KDM4ECHRNA7HTR3A | |
| SCHEMBL984359 | 0.74 | MAPK1 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283622-B1 | MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO | HOFFMANN LA ROCHE (CH) | 2019-07-03 | — | — | EP | disclosed |
| US-10017749-B2 | Mutant transaminases as well as methods and uses relating thereto | HOFFMAN-LA ROCHE INC. (US) | 2018-07-10 | — | — | US | disclosed |
| EP-3283622-A1 | MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO | F. Hoffmann-La Roche AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166120-A1 | MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO | F. HOFFMANN-LA ROCHE AG (CH) | 2016-10-20 | — | — | WO | disclosed |
| US-20160304843-A1 | MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO | HOFFMANN-LA ROCHE INC. (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017749-B2 | Mutant transaminases as well as methods and uses relating thereto | GOT1, GOT2, OAT | ELOVL6 1741/4885L3MBTL3 1525/4885L3MBTL1 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.