Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
| ▸ | MMP16 | P51512 | 1/20 | 0.32 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097608 | 0.84 | LMNA (0.35) | ELANEALDH1A1SMN1; SMN2LMNACA1 | |
| SCHEMBL5696087 | 0.84 | LMNA (0.35) | ELANEALDH1A1SMN1; SMN2LMNACA1 | |
| SCHEMBL1054675 | 0.82 | TDP1 (0.34) | ELANEALDH1A1GAAPKM | |
| SCHEMBL1058381 | 0.80 | TK1 (0.37) | — | |
| SCHEMBL1097419 | 0.80 | ELANE (0.34) | ELANEALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL1060591 | 0.78 | POLB (0.38) | ALDH1A1 | |
| SCHEMBL20394055 | 0.77 | TK1 (0.37) | — | |
| SCHEMBL20394057 | 0.77 | TK1 (0.37) | — | |
| SCHEMBL28749276 | 0.77 | TK1 (0.37) | — | |
| SCHEMBL1097107 | 0.77 | TK1 (0.37) | ELANEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053199-B2 | Nucleoside analogs and oligonucleotide derivatives containing these analogs | Imanishi, Takeshi (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040192918-A1 | Novel nucleoside analogs and oligonucleotide derivatives containing these analogs | IMANISHI, TAKESHI (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1314734-A1 | NOVEL NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE DERIVATIVES CONTAINING THESE ANALOGS | Imanishi, Takeshi (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192918-A1 | Novel nucleoside analogs and oligonucleotide derivatives containing these analogs | DCLRE1B, POLB, POLR1E | ELANE 2773/4885ALDH1A1 1636/4885GAA 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.