Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LIG1 | P18858 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.80 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.80 | HPGD (0.60) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL30216506 | 0.75 | LIG1 (0.53) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL4590099 | 0.75 | ALDH1A1 (0.50) | HPGDHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL930326 | 0.75 | LIG1 (0.53) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL7764770 | 0.74 | HPGD (0.55) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL3800333 | 0.74 | HPGD (0.55) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL580084 | 0.72 | HPGD (0.53) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL28427811 | 0.72 | HPGD (0.53) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL910763 | 0.72 | HPGD (0.53) | HPGDTSHRMAPK1HSD17B10LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053199-B2 | Nucleoside analogs and oligonucleotide derivatives containing these analogs | Imanishi, Takeshi (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040192918-A1 | Novel nucleoside analogs and oligonucleotide derivatives containing these analogs | IMANISHI, TAKESHI (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1314734-A1 | NOVEL NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE DERIVATIVES CONTAINING THESE ANALOGS | Imanishi, Takeshi (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192918-A1 | Novel nucleoside analogs and oligonucleotide derivatives containing these analogs | DCLRE1B, POLB, POLR1E | HPGD 2100/4885TSHR 3182/4885MAPK1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.