Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446457 | 1.00 | SLC6A5 (0.59) | SLC6A5DNM1MEN1KMT2AFAAH | |
| SCHEMBL20414960 | 0.93 | SLC6A5 (0.70) | SLC6A5MEN1KMT2AFAAHDEGS1 | |
| SCHEMBL19557856 | 0.92 | SLC6A5 (0.48) | SLC6A5DNM1MEN1KMT2AFAAH | |
| SCHEMBL27798454 | 0.87 | LMNA (0.52) | SLC6A5MEN1KMT2APLA2G2CPLA2G10 | |
| SCHEMBL3791704 | 0.87 | LMNA (0.52) | SLC6A5MEN1KMT2APLA2G2CPLA2G10 | |
| SCHEMBL23505651 | 0.86 | FAAH (0.58) | DNM1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL27676612 | 0.86 | FAAH (0.58) | DNM1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL27656564 | 0.86 | FAAH (0.58) | DNM1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL27676604 | 0.86 | FAAH (0.58) | DNM1MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL23505641 | 0.86 | FAAH (0.58) | DNM1MEN1KMT2AFAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060222650-A1 | Broad spectrum pyrogenic antagonists and vaccines directed against pyrogenic exotoxins | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-10-05 | — | — | US | disclosed |
| US-7060277-B2 | Broad spectrum antagonists and vaccines directed against pyrogenic exotoxins | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-06-13 | — | — | US | disclosed |