Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879473 | 0.85 | TDP1 (0.42) | LMNAGAAMAOBTDP1L3MBTL1 | |
| SCHEMBL8976466 | 0.83 | PTGER4 (0.51) | LMNAGAAALDH1A1GLATDP1 | |
| SCHEMBL5521213 | 0.79 | LMNA (0.45) | LMNAGAAALDH1A1MAOBTDP1 | |
| SCHEMBL8732326 | 0.76 | PTGER4 (0.42) | LMNAMAOBTDP1L3MBTL1PTGER4 | |
| SCHEMBL8732315 | 0.76 | PTGER4 (0.42) | LMNAMAOBTDP1L3MBTL1PTGER4 | |
| SCHEMBL9353319 | 0.76 | MAOB (0.35) | ALDH1A1MAOBTDP1KDM1ATSHR | |
| SCHEMBL10597879 | 0.75 | LMNA (0.45) | LMNAGAAMAOBTDP1L3MBTL1 | |
| SCHEMBL5879432 | 0.75 | ACHE (0.38) | ALDH1A1GLAMAPTMAPK1PTPN1 | |
| SCHEMBL10481838 | 0.74 | MAPT (0.50) | LMNAGAAALDH1A1MAOBTDP1 | |
| SCHEMBL7708537 | 0.74 | TDP1 (0.57) | LMNAGAAALDH1A1GLAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | LMNA 3547/4885GAA 2926/4885ALDH1A1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.