Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879473 | 0.91 | TDP1 (0.42) | PTGER4PTGER3PTGER2PTGER1HTR1A | |
| SCHEMBL8732326 | 0.84 | PTGER4 (0.42) | PTGER4PTGER3PTGER2PTGER1HTR1A | |
| SCHEMBL8732315 | 0.84 | PTGER4 (0.42) | PTGER4PTGER3PTGER2PTGER1HTR1A | |
| SCHEMBL5879437 | 0.83 | LMNA (0.40) | PTGER4PTGER3PTGER2PTGER1ALDH1A1 | |
| SCHEMBL9857320 | 0.80 | SLC6A2 (0.48) | PTGER4PTGER3PTGER2HTR1ABCHE | |
| SCHEMBL21772327 | 0.80 | ALDH1A1 (0.42) | HTR1AALDH1A1GLATDP1LMNA | |
| SCHEMBL8592447 | 0.79 | ALDH1A1 (0.63) | PTGER4PTGER3PTGER2PTGER1HTR1A | |
| SCHEMBL12670343 | 0.78 | L3MBTL1 (0.36) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL18716386 | 0.78 | HTR1A (0.61) | PTGER4PTGER3PTGER2PTGER1HTR1A | |
| SCHEMBL29157698 | 0.77 | ALDH1A1 (0.40) | ALDH1A1GLATDP1LMNASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480905-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0565732-A1 | BENZODIOXANE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-10-20 | — | — | EP | disclosed |