Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879463 | 0.92 | POLB (0.76) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL24478022 | 0.88 | GABRA1 (0.49) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL5879452 | 0.86 | POLB (0.46) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL16885522 | 0.83 | POLB (0.55) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL9618035 | 0.83 | POLB (0.58) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL11325102 | 0.81 | POLB (0.56) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL21177757 | 0.80 | POLB (0.55) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL8769752 | 0.79 | POLB (0.71) | POLBTSHRMAPK1GABRA1GABRB2 | |
| SCHEMBL11325103 | 0.79 | POLB (0.57) | POLBMAPK1GABRA1GABRB2CNR2 | |
| SCHEMBL3958628 | 0.78 | GABRA1 (0.55) | POLBGABRA1GABRB2ALOX5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | POLB 4413/4885TSHR 4303/4885MAPK1 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.