Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879449 | 0.92 | POLB (0.59) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL29375900 | 0.87 | POLB (1.00) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL28231 | 0.87 | POLB (1.00) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL3403169 | 0.87 | POLB (1.00) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL29420401 | 0.87 | POLB (1.00) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL13356448 | 0.84 | POLB (0.88) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL24478022 | 0.83 | GABRA1 (0.49) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL9661550 | 0.81 | POLB (0.54) | POLBALDH1A1PTGS1TSHRMAPK1 | |
| SCHEMBL3342564 | 0.81 | POLB (0.88) | POLBGABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL5879452 | 0.79 | POLB (0.46) | POLBGABRA1GABRB2ALOX5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | POLB 4413/4885GABRA1 1655/4885GABRB2 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.