Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.45 |
| ▸ | ITGAV | P06756 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879557 | 0.94 | ITGB3 (0.44) | ITGB3ITGAVALDH1A1CDC25AHSD17B10 | |
| SCHEMBL5879653 | 0.91 | ITGB3 (0.46) | ITGB3ITGAVALDH1A1HSD17B10KDM4E | |
| SCHEMBL5879648 | 0.89 | CDC25A (0.44) | ITGB3ITGAVALDH1A1CDC25AHSD17B10 | |
| SCHEMBL5879654 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVALDH1A1CDC25AHSD17B10 | |
| SCHEMBL5879871 | 0.87 | ALDH1A1 (0.50) | ITGB3ITGAVALDH1A1KDM4EUSP2 | |
| SCHEMBL5879798 | 0.86 | ALDH1A1 (0.49) | ITGB3ITGAVALDH1A1KDM4EUSP2 | |
| SCHEMBL5879914 | 0.85 | ITGB3 (0.47) | ITGB3ITGAVALDH1A1KDM4EUSP2 | |
| SCHEMBL5879559 | 0.83 | HTR1A (0.46) | ITGB3ITGAVALDH1A1KDM4EUSP2 | |
| SCHEMBL5879626 | 0.79 | ITGB3 (0.48) | ITGB3ITGAVKDM4EUSP2CASP1 | |
| SCHEMBL5879590 | 0.78 | ITGB3 (0.54) | ITGB3ITGAVALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |