Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.51 |
| ▸ | ITGAV | P06756 | 18/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879543 | 0.83 | ITGB3 (0.76) | ITGB3ITGAV | |
| SCHEMBL5879746 | 0.71 | ITGB3 (0.65) | ITGB3ITGAVCDC25A | |
| SCHEMBL5879576 | 0.70 | ITGB3 (0.54) | ITGB3ITGAVCDC25A | |
| SCHEMBL27730470 | 0.69 | MAPT (0.39) | ITGB3ITGAV | |
| SCHEMBL5879684 | 0.69 | ITGB3 (0.73) | ITGB3ITGAVCDC25A | |
| SCHEMBL816698 | 0.68 | MAPK1 (0.57) | — | |
| SCHEMBL5879512 | 0.68 | ITGB3 (0.44) | ITGB3ITGAVCDC25A | |
| SCHEMBL5879566 | 0.68 | ITGB3 (0.54) | ITGB3ITGAV | |
| SCHEMBL5879533 | 0.67 | ITGB3 (0.55) | ITGB3ITGAV | |
| SCHEMBL27710132 | 0.67 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |