Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.59 |
| ▸ | ITGAV | P06756 | 17/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879515 | 0.91 | ITGB3 (0.61) | ITGB3ITGAV | |
| SCHEMBL5879914 | 0.85 | ITGB3 (0.47) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879794 | 0.84 | ITGB3 (0.63) | ITGB3ITGAV | |
| SCHEMBL5879556 | 0.83 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL5879559 | 0.83 | HTR1A (0.46) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879583 | 0.80 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL5879581 | 0.77 | ITGB3 (0.66) | ITGB3ITGAV | |
| SCHEMBL5879871 | 0.77 | ALDH1A1 (0.50) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879954 | 0.77 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL5879798 | 0.76 | ALDH1A1 (0.49) | ITGB3ITGAVKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |