Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879755 | 1.00 | CSNK1D (0.43) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5879913 | 0.87 | FFAR2 (0.41) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5879917 | 0.87 | FFAR2 (0.41) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5880161 | 0.87 | CYP1A2 (0.49) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5880163 | 0.87 | CYP1A2 (0.49) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5879821 | 0.85 | CSNK1D (0.42) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5879826 | 0.85 | CSNK1D (0.42) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5880182 | 0.85 | MEN1 (0.47) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5880186 | 0.85 | MEN1 (0.47) | CSNK1DLMNAFFAR2NPSR1CYP1A2 | |
| SCHEMBL5879892 | 0.84 | LMNA (0.43) | CSNK1DLMNAFFAR2NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |