Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879913 | 1.00 | FFAR2 (0.41) | FFAR2CSNK1DCTHTRPV1KDM4E | |
| SCHEMBL5879862 | 0.90 | MAPT (0.43) | FFAR2CSNK1DKDM4ENPSR1CYP1A2 | |
| SCHEMBL5879858 | 0.90 | MAPT (0.43) | FFAR2CSNK1DKDM4ENPSR1CYP1A2 | |
| SCHEMBL5879841 | 0.88 | KMT2A (0.49) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5879837 | 0.88 | KMT2A (0.49) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5879755 | 0.87 | CSNK1D (0.43) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5879752 | 0.87 | CSNK1D (0.43) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5879897 | 0.87 | LMNA (0.44) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5879903 | 0.87 | LMNA (0.44) | FFAR2CSNK1DKDM4EPKMNPSR1 | |
| SCHEMBL5880168 | 0.86 | SGK1 (0.44) | FFAR2KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |