Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879825 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5880198 | 0.89 | MAPT (0.55) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5880202 | 0.89 | MAPT (0.55) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5879834 | 0.88 | MAPK1 (0.53) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL6378261 | 0.88 | MAPK1 (0.53) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5880199 | 0.82 | LMNA (0.47) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5880203 | 0.82 | LMNA (0.47) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5879846 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5879842 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL5880113 | 0.79 | SGK1 (0.48) | ALDH1A1MAPTLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |